Liver Fibrosis

Liver Fibrosis

Liver Fibrosis

Overview

Liver fibrosis occurs when the liver is repeatedly damaged, leading to the formation of scar tissue as part of the healing process. Over time, this scar tissue can replace healthy liver tissue, impairing liver function. Common causes include chronic hepatitis, alcohol abuse, and non-alcoholic fatty liver disease (NAFLD). Early diagnosis and intervention are crucial to prevent progression to cirrhosis and liver failure. With innovative treatments like stem cell therapy, there is hope for reversing liver damage and improving outcomes.

Symptoms of Liver Fibrosis

In its early stages, liver fibrosis often has no noticeable symptoms. As the condition progresses, symptoms may include:


Fatigue: Persistent tiredness or weakness.


Abdominal pain or discomfort: Especially in the upper right side.


Swelling: In the abdomen (ascites) or legs (edema).


Jaundice: Yellowing of the skin and eyes.


Unexplained weight loss: Loss of appetite or muscle wasting.


Easy bruising or bleeding: Due to impaired liver function.


Dark urine or pale stools: Changes in urine or stool color.

When to See a Doctor

Consult a healthcare professional if you experience:


Persistent fatigue or abdominal pain.


Swelling in the abdomen or legs.


Yellowing of the skin or eyes.


Unexplained weight loss or changes in urine/stool color.


Easy bruising or bleeding.

Early diagnosis and treatment are essential to prevent complications and improve liver health.

Causes of Liver Fibrosis

Liver fibrosis can result from various factors, including:


Chronic viral infections:


Hepatitis B or C.


Alcohol abuse:


Long-term excessive alcohol consumption.


Non-alcoholic fatty liver disease (NAFLD):


Associated with obesity, diabetes, and metabolic syndrome.


Autoimmune diseases:


Autoimmune hepatitis or primary biliary cholangitis.


Toxins or medications:


Prolonged exposure to toxins or certain drugs.


Genetic disorders:


Hemochromatosis, Wilson’s disease, or alpha-1 antitrypsin deficiency.

How Liver Fibrosis is Diagnosed

Diagnosing liver fibrosis involves a combination of tests and evaluations, including:


Medical history: Reviewing symptoms, alcohol consumption, and risk factors.


Physical examination: Checking for signs of liver enlargement or tenderness.


Blood tests:


Liver function tests to assess enzyme levels (ALT, AST).


Tests for viral hepatitis or autoimmune markers.


Imaging tests:


Ultrasound: To detect liver abnormalities.


CT scan or MRI: For detailed images of the liver.


Elastography: To measure liver stiffness and assess fibrosis.


Liver biopsy:


A small sample of liver tissue is taken to evaluate the extent of fibrosis and inflammation.

Treatment Options for Liver Fibrosis

The goal of treatment is to address the underlying cause, reduce inflammation, and prevent further liver damage. Treatment options include:


Lifestyle changes:


Weight loss: For patients with NAFLD or obesity.


Alcohol avoidance: Complete abstinence for those with alcohol-related liver disease.


Healthy diet: Rich in fruits, vegetables, whole grains, and lean proteins.


Regular exercise: To improve overall health and liver function.


Medications:


Antiviral drugs: For hepatitis B or C.


Corticosteroids or immunosuppressants: For autoimmune hepatitis.


Vitamin E or pioglitazone: For non-alcoholic steatohepatitis (NASH).


Monitoring and follow-up:


Regular check-ups to monitor liver health and disease progression.


Innovative treatments:


Stem cell therapy: At Concord Stem Cell Limited, we are exploring the potential of stem cells to repair damaged liver tissue, reduce inflammation, and reverse fibrosis. Stem cell therapy offers hope for regenerating healthy liver cells and improving liver function.


Liver transplant:


For advanced cases of cirrhosis or liver failure, a liver transplant may be necessary.


Why Choose Concord Stem Cell Limited?

As a DGDA-approved stem cell manufacturing and practicing company in Dhaka, Bangladesh, Concord Stem Cell Limited is at the forefront of innovative treatments for liver fibrosis. Our team of experts combines advanced medical research with compassionate care to provide hope and improved outcomes for patients.


If you or a loved one is living with liver fibrosis, contact us today to learn more about our cutting-edge treatment options, including stem cell therapy, and how we can support your journey to better liver health.

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