Diabetic nephropathy develops when high blood sugar levels damage the small blood vessels in the kidneys, impairing their function over time. It is more common in individuals with poorly controlled diabetes and can progress to end-stage renal disease (ESRD) if left untreated. Early detection and management are crucial to slow disease progression and prevent complications. With innovative treatments like stem cell therapy, there is hope for improving kidney function and quality of life.

In its early stages, diabetic nephropathy often has no noticeable symptoms. As the condition progresses, symptoms may include:

Swelling: In the legs, ankles, feet, or hands (edema).

Foamy urine: Caused by excess protein (proteinuria).

Fatigue: Persistent tiredness or weakness.

Nausea or vomiting: Due to the buildup of waste products in the blood.

Loss of appetite: Reduced desire to eat.

Difficulty concentrating: Mental fog or confusion.

High blood pressure: Often difficult to control.

Frequent urination: Especially at night.

Diabetic nephropathy is primarily caused by prolonged high blood sugar levels, which damage the kidneys' filtering system. Other contributing factors include:

Poor blood sugar control: Consistently high glucose levels.
High blood pressure: Damages blood vessels in the kidneys.
Duration of diabetes: The longer you have diabetes, the higher the risk.
Genetic factors: A family history of kidney disease.
Lifestyle factors: Smoking, obesity, and a high-sodium diet.

Diagnosing diabetic nephropathy involves a combination of tests and evaluations, including:

Urine tests:

Albumin-to-creatinine ratio (ACR): To detect protein in the urine.

24-hour urine collection: To measure protein levels over a day.

Blood tests:

Serum creatinine: To assess kidney function and estimate glomerular filtration rate (eGFR).

Imaging tests:

Ultrasound: To check the size and structure of the kidneys.

Kidney biopsy:

A small sample of kidney tissue is taken to assess damage.

The goal of treatment is to slow disease progression, manage symptoms, and prevent complications. Treatment options include:

Blood sugar control:

Maintaining target blood sugar levels through medication, diet, and exercise.

Blood pressure management:

ACE inhibitors or ARBs: Medications to lower blood pressure and reduce proteinuria.

Lifestyle changes:

Healthy diet: Low in sodium, protein, and processed foods.

Regular exercise: To improve overall health and blood sugar control.

Smoking cessation: To reduce further kidney damage.

Medications:

SGLT2 inhibitors: To lower blood sugar and protect kidney function.

Diuretics: To reduce fluid retention and swelling.

Innovative treatments:

Stem cell therapy: At Concord Stem Cell Limited, we are exploring the potential of stem cells to repair damaged kidney tissue, reduce inflammation, and improve kidney function. Stem cell therapy offers hope for managing diabetic nephropathy and enhancing quality of life.

Why Choose Concord Stem Cell Limited?

As a DGDA-approved stem cell manufacturing and practicing company in Dhaka, Bangladesh, Concord Stem Cell Limited is at the forefront of innovative treatments for diabetic nephropathy. Our team of experts combines advanced medical research with compassionate care to provide hope and improved outcomes for patients.

If you or a loved one is living with diabetic nephropathy, contact us today to learn more about our cutting-edge treatment options, including stem cell therapy, and how we can support your journey to better kidney health.